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Microplastics Could Be Weakening Your Bones, Research Suggests

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Microplastics Could Be Weakening Your Bones, Research Suggests


Microplastics could be a factor in driving up cases of osteoporosis worldwide, according to recently published research. The study reveals that when these tiny plastic particles enter the body, they disrupt the functioning of bone marrow stem cells, which are essential for maintaining and repairing bone tissue.

Throughout your life, your bones are replenished. Osteoporosis is a condition where this process goes wrong, with the breakdown of bone outstripping the rate at which it is replaced. This leads to bones weakening over time and becoming more likely to fracture. The condition has many risk factors—age, sex, medications, diet, smoking and drinking, and genetics are all known to influence it—with the disease developing slowly over time. Often people don’t realize they have the condition until they break a bone.

This new analysis, published in the journal Osteoporosis International, adds exposure to microplastics as a potential new risk factor. The research reviewed 62 scientific articles that had run various laboratory and animal tests on the possible effects of micro- and nanoplastics on bone. Analysis of lab experiments showed that microplastics stimulate the formation of osteoclasts, cells created by stem cells in the bone marrow that degrade bone tissue to promote resorption, the process in which the body breaks down and eliminates old or damaged bone.

The study also found that, in relation to bones, plastic particles can reduce the viability of cells, induce premature cellular aging, modify gene expression, and trigger inflammatory responses. The combination of these effects generates an imbalance in which osteoclasts destroy more bone tissue than is regenerated, causing an accelerated weakening of bone structure.

When then looking at animal studies, the researchers found that the accumulation of microplastics in the body decreases the white blood cell count—which is suggestive of alterations in bone marrow function. In addition, these animal studies suggested that the impact of microplastics on osteoclasts may be associated with deterioration of bone microstructure and the formation of irregular structures of cells, increasing the risk of bone fragility, deformities, and fractures.

“In this study, the adverse effects observed culminated, worryingly, in the interruption of the animals’ skeletal growth,” said coauthor Rodrigo Bueno de Oliveira in a press release. “The potential impact of microplastics on bones is the subject of scientific studies and isn’t negligible.”

Oliveira, who is the coordinator of the Laboratory for Evaluation of Mineral and Bone Disorders in Nephrology at the State University of Campinas in Brazil, is now working with his team to further prove in practice the relationship between exposure to microplastics and bone deterioration. This research will begin by evaluating the effects of microplastic particles on rodents’ femurs.

“Although osteometabolic diseases are relatively well understood, there’s a gap in our knowledge regarding the influence of microplastics on the development of these diseases. Therefore, one of our goals is to generate evidence suggesting that microplastics could be a potential controllable environmental cause to explain, for example, the increase in the projected number of bone fractures,” Oliveira said.

Microplastics and nanoplastics are small fragments of plastic—some so small that they’re invisible to the naked eye—that become detached from everyday objects when sunlight, wind, rain, seawater, or abrasion degrade them. The main difference between the two lies in their size: microplastics measure from 1 micrometer (one-thousandth of a millimeter) to 5 millimeters, while nanoplastics are smaller than 1 micrometer. These particles have been detected all over the world in natural environments, as well as throughout the human body and in meat, water, and various agricultural products.

Studies have started to show that this type of plastic contamination can damage health. Experts argue that this means the world urgently needs to reduce its use of plastics. Every year more than 500 million tons of the material are produced worldwide, but only 9 percent is recycled, with much of the remainder spreading into the environment and degrading.

This story originally appeared on WIRED en Español and has been translated from Spanish.



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Need One Pair for Hiking, Traveling, and Working Out? Try Gravel Running Shoes

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Need One Pair for Hiking, Traveling, and Working Out? Try Gravel Running Shoes


HOKA’s max-stacked Rocket X Trail combines road race shoe energy with boosted grip from a 3-mm lugged outsole. If you’re looking for a fast shoe to go on the attack, this is it. It’s also fantastic for all round comfort. In testing, I laced up the Rocket X Trail and ran 3 hours (just short of 19 miles) fresh out of the box, across roads, forest gravel trails, some grass and through some serious water. It delivered efficiency and energy whether I was moving at marathon pace or with heavier, tired, ragged footfalls in the latter miles.

The rockered, supercritical midsole uses HOKA’s liveliest foam, similar to those you find in its race-ready road shoes, along with a carbon plate. That combines for a really fun ride that’s smooth, springy and fast and really consistent. It’s also highly cushioned, so you will sacrifice a lot of ground feel for that big stack springy softness. It’s also less stable over very lumpy terrain. But on open, flat, runnable mixed terrain, it’s excellent.

The lightweight uppers have a race-shoe-ready feel and after running through ankle-deep flooded sections, they shed water really quickly. This is a pricey road-to-trail shoe, it’s versatile and there’s plenty of winter road potential, too.

Specs
Weight 9.45 oz
Heel-to-toe drop 6 mm
Lug depth 3 mm



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If a Garmin Is Too Expensive, Consider Suunto’s Latest Adventure Watch

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If a Garmin Is Too Expensive, Consider Suunto’s Latest Adventure Watch


It’s always pleasing to see an array of physical buttons, and you get sizable ones too. You’re not going to miss these wide flat ones even when picking the pace up. The silicone strap has a nice stretch to it and while the button clasp is a bit awkward to get into place, this watch does not budge.

Suunto has jumped on the flashlight trend, with an LED light strip sat on the front of the case. You can adjust brightness levels and there’s SOS and alert modes to emit a very noticeable pulsating light pattern. This is a light I found useful rooting around indoors as well as on nighttime outings.

The biggest change is the introduction of a 1.5-inch, 466 x 466 AMOLED display. This replaces the dull, albeit very visible, memory-in-pixel (MIP) display. Suunto also ditched the solar charging that did require spending a significant amount of time outside to reap its battery benefits.

Adding AMOLED screens to outdoor watches has been contentious. The older MIP displays are just more power-efficient. The Vertical 2 is down by about 10 days from the older Vertical for what Suunto calls daily use.

Still, even if you’re putting its tracking and mapping features to use, you’re not going to be reaching for the charger every few days. After two hours of tracking in optimal GPS mode, the battery only dropped by 2 to 3 percent. The battery drop outside of tracking is also small and the standby performance is excellent as well.

Software Updates

Photograph: Michael Sawh

A more streamlined set of smartwatch features helps reserve battery for when it really matters. Unfortunately, I probably got better battery life because you don’t get phone notifications or responses if it’s paired to an iPhone instead of an Android. There’s also no onboard music player, but you do get a pretty slick set of music playback controls that are accessible during tracking.



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Electronic health records are still creating issues for patients | Computer Weekly

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Electronic health records are still creating issues for patients | Computer Weekly


Every NHS trust in England needs an electronic patient record (EPR) system in place by March 2026, as part of a government push to digitise the healthcare system.

In many ways, this is long overdue: some trusts have still been using pen-and-paper record-keeping until very recently. 

EPRs have the potential to massively improve efficiency in the NHS. If working properly, they allow doctors to keep all of their records in one place, speed up prescribing and diagnostics, and make it easier for patients to access their own health information.

But these roll-outs have not been without problems. Concerns have been raised about how far these benefits can actually be realised. Some NHS trusts have experienced issues with integrating new systems and training staff on how to use them.

In the extreme, there have been reports of EPRs creating new problems for hospitals, with evidence suggesting these systems may have contributed to serious harm and even deaths among patients.

NHS trusts have been put in charge of procuring their own EPRs, meaning there are numerous different technology companies involved. Some providers of these systems are large US firms. This includes Oracle Health, provided by the Larry Ellison-led tech giant, and Epic, a tech firm based in Wisconsin.

Contracts can run into nine figures: Guy’s and St Thomas’, a trust in South London, launched a £450m system from Epic in late 2023. Some parts of the NHS have been using them for more than a decade, but a handful are still set to miss the government’s March deadline.

Data access

Pritesh Mistry is a fellow at the King’s Fund, where he researches the impact of digital transformation in the NHS. He says it has had “both positive and negative impacts”.

“In the last few years, we’ve seen doubling down on the focus around digital records,” says Mistry. These are now in place in more than 90% of all trusts, and every GP practice.

“That means we’ve now got [new] data that’s within the healthcare system, which allows us to do other things, like treat populations, and understand and track patient safety,” he says.

Despite this, he cautions some patients are still struggling to get hold of their own data.

“We’ve got a lot of data that’s in silos,” says Mistry. “It doesn’t flow. That’s the biggest challenge: making the data accessible and usable for patients and healthcare professionals to be able to provide care in a way that is joined up and meets with modern expectations.”

He says complaints with new technology haven’t just come from patients.

“We need to recognise that staff are really frustrated,” says Mistry. “Software often crashes. Computers are really slow, and technology adds to their workload, instead of simplifying things.” He caveats that some parts of the NHS are better than others on this.

Safeguarding patient data

Mistry adds that there are safeguards in place to ensure patient data isn’t ending up where it shouldn’t be – such as through data protection rules and procurement requirements.

However, he warns that “we need to make sure we move with the times in terms of what technology is available”. Mistry is more concerned about medical staff inadvertently putting personal information into a large language model, for instance.

“Digital exclusion remains a barrier as well,” he says, adding that these systems have the potential to widen inequalities in healthcare. Those less able to use new technology might struggle to access their records.

“People tend to assume it’s old people [who are most impacted], but that isn’t necessarily true,” says Mistry, instead highlighting the impact of poverty and deprivation, with some still unable to afford internet access.

He argues the NHS should be working to meet people where they are, and provide more “tailored” technology services.

Patient safety

Nick Woodier is a doctor and investigator at the Health Services Safety Investigations Body (HSSIB), which looks into issues with healthcare in the UK. He sees problems arising from how EPRs are deployed by trusts, especially when medical staff overestimate their capabilities.

He uses the example of prescribing medicines: “There’s an assumption that these electronic prescribing systems will stop you [from] doing something catastrophic.”

But this isn’t always the case. In one investigation, the HSSIB found a child had been prescribed nearly 10 times the recommended dose of an anti-coagulant medication, with doctors having assumed the EPR would flag an issue. The child ended up with a bleed on their brain.

Woodier also worries hospitals are not always picking up on when these systems are at fault.

“We will often see where incidents have happened and the contribution of the electronic system has not been recognised,” he says.

Woodier sees this as coming from a culture which prefers to put the blame for safety failures on individuals.

A 2024 investigation by the BBC found there were more than 126 instances of serious harm registered by NHS trusts across 31 trusts, including three deaths related to EPR problems.

The HSSIB has also encountered problems from patients being unable to access their digital records.

“We’ve seen in general practice, for example, some patients telling us that they’ve gone without care – because in their mind, they thought the only way they could access their GP was to fill in an electronic form,” says Woodier.

A spokesperson for NHS England says EPRs are “already having a significant impact on improving safety and care for patients”, for instance, by helping to identify conditions such as sepsis, and preventing medication errors. 

“They have replaced outdated and often less-safe paper-based systems, and we are working closely with NHS trusts to ensure they are implemented safely alongside other systems with appropriate training – and are used to the highest quality and safety standards,” the spokesperson adds.

Interoperability

The EPR roll-out has also been criticised for problems with “interoperability” – the ability of different programs and modes of data collection to converse with each other. The patchwork of different systems used by different trusts means data stored in one system might not be useful for a system used by a different part of the NHS.

Woodier says this often happens in communications between hospitals and GP surgeries. This can involve someone manually inputting information from one system to another, which can create risks when data is not being transferred properly, or is missed completely.

“When you introduce a manual operation, that risk increases,” he warns. “The odds are that at some point, somebody won’t do the right thing, because that’s the reality of being human.”

Alex Lawrence, a fellow at the Health Foundation, describes interoperability as a “significant challenge”, which the NHS and technology companies have been “grappling with for a really long time”.

“Some trusts have found it much harder to access their own EPR data than they anticipated, because of where that data is stored,” she adds, referring to research the organisation carried out in 2024.

“If it’s taking you days to pull the data that you need, then it’s already not going to be useful for a lot of the purposes that you might want it for.”

However, Lawrence adds that there have been some steps made in the right direction, notably with the Data (Use and Access) Act, which was passed last year.

“The government is making information standards mandatory for EPR providers, as well as trusts, with the Secretary of State potentially having more powers to enforce those standards,” she says.

The longer term

Going forward, Lawrence would like to see a system involving “patients being empowered with access to their own data, and as far as appropriate, clinicians being able to see all of the history that they need for their patients”.

In an ideal system, different parts of the healthcare system would be able to “share a patient’s data where necessary and appropriate, in an easy and timely way”.

She says they have the “potential to offer enormous value”, but much of their functionality is going unused. “What our qualitative research suggested was that a lot of these systems are still functioning as digital notebooks,” says Lawrence.

Matthew Taylor is the head of the NHS Confederation and NHS Providers, membership bodies for healthcare organisations.

“NHS leaders say the gap between trusts on digital maturity is still stark – and it’s shaping how quickly organisations can move to modern EPRs,” he says.

This gap – combined with the organisational complexity of the healthcare system – means interoperability has “long been a thorn in the NHS’s side”.

Taylor adds that EPRs are not a “once-and-done” job, and argues they will result in savings in the long term, but that it may take around five years to see the benefits.

“Hospitals are housing a huge amount of paper records, and the cost of storing, retrieving and managing those records can run into millions of pounds each year,” he says.

These systems are part of a larger picture, and one facet of the conversation, around the use of artificial intelligence in the NHS. AI models for areas such as research and diagnostics will require extensive and standardised medical data.

Mistry warns these AI tools operate on the basis of “garbage in, garbage out”.

“There is a risk that we roll out AI tools without the underpinning data quality it needs,” he says, adding that this could exacerbate inequalities or biases from using AI.

As Woodier puts it: “We’ve got organisations who are still using archaic computers, have got infrastructure that’s not working, are still on old web systems, or have EPRs that don’t talk to each other. A few [trusts] don’t have EPRs.

“So, actually, are we trying to run before we’ve even managed to walk?”



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