Business
Pfizer boosts obesity drug prospects with $7.3 billion deal to buy Metsera

Thomas Fuller | SOPA Images | Lightrocket | Getty Images
Pfizer on Monday said it would buy weight loss drugmaker Metsera in an up to $7.3 billion deal, including future payments, as it scrambles to win a slice in the booming obesity drug market.
Pfizer said it will pay an initial $47.50 a share in cash for Metsera, a nearly 43% premium to the biotech company’s Friday’s closing price of $33.32. That gives the deal an enterprise value of $4.9 billion.
The pact also includes a contingent value right worth up to $22.50 a share based on potential clinical and regulatory achievements for Metsera’s medicines, which could bring the total value to $70 a share.
The deal is expected to close at the end of the year. Shares of Metsera rose more than 60% in premarket trading on Monday, while Pfizer’s stock rose more than 1%.
The move comes after a string of setbacks for Pfizer in the obseity space. The pharmaceutical giant struggled to develop its own lead obesity drug candidate, danuglipron, before deciding to scrap it entirely in April due to safety concerns. Pfizer also discontinued a different once-daily pill in June 2023 due to elevated liver enzymes in patients who received it.
Pfizer has earlier-stage obesity drugs in its pipeline that work in different ways, but the company has faced mounting investor pressure to accelerate its push into the market.
The opportunity could be huge. Some analysts expect the weight loss drug space could be worth roughly $100 billion by the 2030s, with room for new rivals to compete with popular injections from Eli Lilly and Novo Nordisk.
Metsera, founded in 2022, brings a pipeline of both oral and injectable treatments with different targets that the company had picked up through its own licensing and acquisition deals. That includes a GLP-1 drug called MET-233i, which helped patients lose up to 8.4% of their weight in 36 days in a small, early-stage trial. Metsera is developing that treatment as a potential once-monthly injectable, meaning that patients can take it less frequently than existing weekly injections.
Metsera’s pipeline also includes a monthly drug targeting a hormone called amylin, along with two oral GLP-1 candidates “expected to begin trials imminently,” Pfizer said in a release.
“The proposed acquisition of Metsera aligns with our focus on directing our investments to the most impactful opportunities and propels Pfizer into this key therapeutic area,” Pfizer CEO Albert Bourla said in a statement. “We are excited to apply our deep cardiometabolic experience and manufacturing and commercial infrastructure to accelerate a portfolio that includes potential best-in-class injectables.”
In a note on Monday, Leerink Partners analyst David Risinger said the firm estimates Metsera’s obesity candidates have the potential to generate more than $5 billion in combined peak annual sales. In a separate note on Monday, JPMorgan analyst Chris Schott said Metsera’s experimental drugs “should accelerate” Pfizer’s entry into the market.
The New York-based Metsera went public this year in one of the biggest biotech listings of 2025. It is among several companies racing to develop next-generation obesity treatments following the success of weekly injections such as Eli Lilly’s obesity drug Zepbound and Novo Nordisk’s rival Wegovy.
Business
Diwali Muhurat Trading 2025: NSE, BSE Announce Timings, Different From Last Year

Last Updated:
The exchange announced that the pre-opening session will take place from 1:30 pm to 1.45 pm

The market will remain closed for regular trading on Diwali, but a special trading window will be open for one hour.
Stock exchanges NSE and BSE will conduct a special Muhurat trading session on Tuesday, October 21, to mark the festival of Diwali, the bourses announced on Monday.
The symbolic trading session will be held between 1:45 pm and 2:45 pm, the stock exchanges said in separate circulars.
Last year, the special Muhurat trading session was held from 6 pm to 7 pm.
The new session also marks the beginning of a new Samvat (Vikram Samvat 2082) — the Hindu calendar year that starts on Diwali — and it is believed that trading during the ‘Muhurat’ or auspicious hour brings prosperity and financial growth for the stakeholders.
The market will remain closed for regular trading on Diwali, but a special trading window will be open for one hour.
The exchange announced that the pre-opening session will take place from 1:30 pm to 1.45 pm.
Market analysts noted that Diwali is considered an auspicious occasion to begin new ventures, and many investors believe participating in the Muhurat trading session brings prosperity throughout the year.
However, with the trading window limited to just an hour, the markets often witness heightened volatility. Analysts added that the significance of the session lies more in its symbolic value than in immediate profitability.
Trading would take place across various segments like equity, commodity derivatives, currency derivatives, equity futures & options, and securities lending & borrowing (SLB) in the same time slot, according to separate circulars issued by the bourses. PTI SP SHW
(This story has not been edited by News18 staff and is published from a syndicated news agency feed – PTI)
September 22, 2025, 20:34 IST
Read More
Business
Gold Prices Hit Record Rs 1.11 Lakh per 10 Grams, Silver Tops Rs 1.33 Lakh/kg As Safe-Haven Demand And Weak Rupee Push Bullion To All-Time Highs

New Delhi: Gold prices in India climbed to unprecedented levels on Monday, with futures trading touching Rs 1,11,750 per 10 grams — a fresh all-time high. The December delivery contract on the Multi Commodity Exchange (MCX) rose by Rs 799 (about 0.72 percent) to reach this peak, as investors reacted to global cues including expected US inflation data and remarks from Federal Reserve officials.
Silver followed suit, with brisk gains across delivery contracts. The March silver futures, for example, surged by Rs 2,446 (nearly 1.86 percent ) to settle at Rs 1,33,582 per kilogram. The December silver contract also breached previous highs, jumping by Rs 2,473 (almost 1.9 percent) to hit Rs 1,32,311/kg.
Analysts believe several factors are pushing precious metal prices upward:
A weaker Indian rupee, which makes imports costlier.
Geopolitical tension and global macroeconomic uncertainty, leading investors to seek safe-haven assets like gold.
Inflation expectations in the US, along with signals from the Fed about possible future rate cuts.
Industrial demand boosting silver — especially for applications in solar panels, electronics, EVs and other green technologies.
Some experts are now forecasting that silver might push toward Rs 1,40,000–Rs 1,50,000 per kg in the near term, depending on supply trends and ongoing demand.
For now, the current price levels mark a new benchmark in the bullion market — signalling both investor caution and eagerness, as global and domestic forces combine to reshape what was already a strong run upward.
Business
Reeves: Gatwick second runway shows Government ‘backing builders, not blockers’

Gatwick Airport’s £2.2 billion second runway plan could create thousands of jobs and help “kickstart the economy”, Chancellor Rachel Reeves said.
In the privately financed project, the West Sussex airport will move its emergency runway 12 metres north, enabling it to be used for departures of narrow-bodied planes such as Airbus A320s and Boeing 737s.
This will enable it to be used for about 100,000 more flights a year.
Ms Reeves said: “This Government promised to kickstart the economy – and we are.
“A second runway at Gatwick means thousands of more jobs and billions more in investment for the economy.”
The Chancellor views the plan as a signal of the Government’s commitment to back “the builders, not the blockers”.
She said: “By slashing red tape and transforming the planning system to get Britain building again we are investing in this country’s renewal and building an economy that works for working people.”
Ms Reeves is keen to seize on any positive news for the economy as she prepares for her November 26 Budget against a backdrop of sluggish growth and inflation remaining stubbornly above target.
The Gatwick scheme has been given the go-ahead by Transport Secretary Heidi Alexander.
She backed the scheme as a “no-brainer” for economic growth, a Government source said, suggesting flights could take off from the new full runway before 2029.
The Cabinet minister is satisfied with adjustments made, covering issues such as noise mitigation and the proportion of passengers who would travel to and from the airport by public transport.
It comes after the Planning Inspectorate initially rejected the airport’s application and earlier this year recommended Ms Alexander should approve the project if the changes were made.
New commitments include a legally binding target for the proportion of passengers who travel to Gatwick by public transport, rather than the airport’s management setting its own targets.
Residents affected by more noise will be able to ask Gatwick to cover the costs for triple-glazed windows.
Homeowners, living directly beneath the new flight routes who choose to sell could have their stamp duty and reasonable moving costs paid, as well as estate agent fees of up to 1% of the purchase price.
Gatwick says its plans will create £1 billion per year in economic benefits, and generate an additional 14,000 jobs.
A Government source told the PA news agency: “With capacity constraints holding back business, trade and tourism, this is a no-brainer for growth.
“This Government has taken unprecedented steps to get this done, navigating a needlessly complex planning system, which our reforms will simplify in future.
“It is possible that planes could be taking off from a new full runway at Gatwick before the next general election.”
The source said the expansion must be delivered in line with climate change commitments and meet strict environmental requirements.
Local campaigners opposed to expansion are concerned about the impact on surface transport, noise, housing provision and wastewater treatment, but the airport insists it has conducted “full and thorough assessments” of those issues.
Cagne, an umbrella aviation community and environment group for Sussex, Surrey and Kent, said it stands ready to serve a judicial review funded by residents and environmental bodies.
The group said: “We know this Government cares little for the environmental impact aviation is having on our planet and Gatwick’s neighbours, but not to demand that Gatwick pays for the infrastructure, the onsite wastewater treatment plant, and noise impact is unlawful in our book.”
The Labour Government’s backing of a third runway at Heathrow Airport in its bid to grow the economy has also drawn criticism from environmental groups and opposition politicians.
The move was welcomed by shadow transport secretary Richard Holden, who accused Labour of delaying the “key” decision.
He said: “This decision should have been made months ago. Labour pledged to go ‘further and faster’ on growth, yet they’ve dithered and delayed at every turn.
“Pushing key decisions down the road has only created uncertainty for businesses and local communities.”
But Green Party leader Zack Polanski said: “Labour keeps wheeling out the same nonsense about growth, but at what cost? What this really means is more pollution, more noise for local communities, and no real economic benefit.”
Stewart Wingate, Vinci Airports managing director for the UK and former Gatwick chief executive, said: “After a lengthy and rigorous planning process, we welcome the Government’s approval of plans to bring our Northern Runway into routine use, ahead of the expected deadline.
“This is another important gateway in the planning process for this £2.2bn investment, which is fully funded by our shareholders and will unlock significant growth, tourism and trade benefits for London Gatwick and the UK and create thousands of jobs.
“As we’ve said previously, it is essential that any planning conditions enable us to realise the full benefits of the project and do not impose unnecessary constraints that make it uneconomic to invest in.
“We now need to carefully examine the details of the planning consent. Once we have done that, we will be able to comment further.”
-
Tech1 week ago
How to Switch to Google Fi
-
Tech1 week ago
The Top 11 Protein Powders, According to My Stomach
-
Tech1 week ago
The Hypershell Pro X Exoskeleton Made My Hikes Feel Easier—Then I Checked My Stats
-
Fashion1 week ago
UK retailer ASOS & ITF sign deal to protect transport workers’ rights
-
Tech1 week ago
The MOTIF Hand: A tool advancing the capabilities of previous robot hand technology
-
Tech7 days ago
How AI Is Upending Politics, Tech, the Media, and More
-
Fashion1 week ago
GHG emissions hit record high in 2024 despite declines in EU, Japan
-
Fashion7 days ago
India’s new GST makes artisan-made ethnic wear costlier