Tech
FDA Approves Pill Version of Wegovy
The US Food and Drug Administration today approved a pill version of the blockbuster anti-obesity drug Wegovy. Made by Novo Nordisk, the pill is taken once a day. The company’s original version of Wegovy is a weekly injection. Both drugs contain the same active ingredient, semaglutide.
“This allows patients with obesity who want to lose weight to have a choice between a once weekly injection or a daily tablet,” says Martin Holst Lange, chief scientific officer at Novo Nordisk.
With the soaring popularity of injectable GLP-1 drugs for weight loss, Novo Nordisk and other pharmaceutical companies have been racing to make effective pill versions that could be preferable for some patients. These drugs mimic a naturally occurring hormone in the body that acts on the brain and gut to promote a feeling of fullness.
In clinical trial results published in the New England Journal of Medicine, participants who took the pill achieved an average weight loss of 13.6 percent by 64 weeks. Nearly 30 percent of people lost 20 percent or more of their weight. The study also showed improvements in cardiovascular disease risk and physical activity levels similar to the injectable version.
While pills can sometimes be a more convenient option, patients may not always take them as prescribed, making them less effective. The clinical trial investigators estimated that in an ideal scenario where participants take the pill every day as prescribed, weight loss would be 16.6 percent—which is similar to results seen with injectable Wegovy.
Novo Nordisk first won approval for an oral semaglutide, sold under the brand name Rybelsus, in 2019 to treat type 2 diabetes. That drug has never been approved for obesity and is not as effective for weight loss as newer GLP-1 medications. The Wegovy pill is essentially a higher-dose version of Rybselsus.
“The efficacy for the obesity pill at the end of the day is driven by dose. Higher doses are required to achieve full weight-loss potential for obesity,” Lange says. The Wegovy pill is 25 milligrams while Rybelsus is 14 milligrams.
The most common side effects of oral Wegovy include nausea and vomiting, which are also side effects of the injectable version.
Novo has not disclosed the exact timeline for the drug’s launch, but Lange says it will be available sometime in the first few months of 2026. Production of the medication is already underway at Novo Nordisk’s US manufacturing sites, and the company expects to have enough of the drug to meet US demand.
Tech
AI Research Is Getting Harder to Separate From Geopolitics
The world’s top AI research conference, the Conference on Neural Information Processing Systems—better known as NeurIPS—became the latest organization this week to become embroiled in a growing clash between geopolitics and global scientific collaboration. The conference’s organizers announced and then quickly reversed controversial new restrictions for international participants after Chinese AI researchers threatened to boycott the event.
“This is a potential watershed moment,” says Paul Triolo, a partner at the advisory firm DGA-Albright Stonebridge who studies US-China relations. Triolo argues that attracting Chinese researchers to NeurIPS is beneficial to US interests, but some American officials have pushed for American and Chinese scientists to decouple their work—especially in AI, which has become a particularly sensitive topic in Washington.
The incident could deepen political tensions around AI research, as well as dissuade Chinese scientists from working at US universities and tech companies in the future. “At some level now it is going to be hard to keep basic AI research out of the [political] picture,” Triolo says.
In its annual handbook for paper submissions, issued in mid-March, NeurIPS organizers announced updated restrictions for participation. The rules stated that the event could not provide services including “peer review, editing, and publishing” to any organizations subject to US sanctions, and linked to a database of sanctioned entities. It included companies and organizations on the Bureau of Industry and Security’s entity list and those on another list with alleged ties to the Chinese military.
The new rules would have affected researchers at Chinese companies like Tencent and Huawei who regularly present work at NeurIPS. The database also includes entities from other countries such as Russia and Iran. The US places limits on doing business with these organizations, but there are no rules around academic publishing or conference participation.
The NeurIPS handbook has since been updated to specify that the restrictions apply only to Specially Designated Nationals and Blocked Persons, a list used primarily for terrorist groups and criminal organizations.
“In preparing the NeurIPS 2026 handbook, we included a link to a US government sanctions tool that covers a significantly broader set of restrictions than those NeurIPS is actually required to follow,” the event’s organizers said in a statement issued Friday. “This error was due to miscommunication between the NeurIPS Foundation and our legal team.”
Before they reversed course, the conference organizers initially said that the new rule was “about legal requirements that apply to the NeurIPS Foundation, which is responsible for complying with sanctions,” adding that it was seeking legal consultation on the issue.
Immediate Backlash
The new rule drew swift backlash from AI researchers around the world, particularly in China, which produces a large quantity of cutting-edge machine learning papers and is home to a growing share of the world’s top AI talent. Several academic groups there issued statements condemning the measure and, more importantly, discouraging Chinese academics from attending NeurIPS in the future. Some urged Chinese academics to contribute instead to domestic research conferences, potentially helping increase the country’s influence in relevant science and tech fields.
The China Association of Science and Technology (CAST), an influential government-affiliated organization for scientists and engineers, said Thursday that it would stop providing funding for Chinese scholars traveling to attend NeurIPS and would use the money instead to support domestic and international conferences that “respect the rights of Chinese scholars.”
CAST also said it will no longer count publications at the 2026 NeurIPS conference as academic achievements when evaluating future research funding. It’s unclear if the organization will reverse course now that NeurIPS has walked back the new rule.
Tech
Iranian Hackers Breached Kash Patel’s Email—but Not the FBI’s
Handala’s second claim, however—that it hacked the FBI—seems, for now, to be fiction. All evidence points to Handala having breached Patel’s older, personal Gmail account. Widely believed to be a “hacktivist” front for Iran’s intelligence agency the MOIS, Handala suggested on its website that the emails contained classified information, but the messages initially reviewed by WIRED didn’t appear to be related to any government work. TechCrunch did find, however, that Patel appears to have forwarded some emails from his Justice Department email account to his Gmail account in 2014.
Handala, which cybersecurity experts have described to WIRED as an “opportunistic” hacker group whose cyberattacks and breaches are often calculated more for their propaganda value than their tactical impacts, has nonetheless made the most of Patel’s embarrassing breach. “To the whole world, we declare: the FBI is just a name, and behind this name, there is no real security,” the group wrote in its statement. “If your director can be compromised this easily, what do you expect from your lower-level employees?”
Handala Hackers Put $50 Million Bounty on Trump and Netanyahu’s Heads
For further evidence of Handala’s bombastic rhetoric, look no further than another post on its website earlier this week (we’re intentionally not linking to it) that offered a $50 million bounty to anyone who could “eliminate” US president Donald Trump and Israeli prime minister Benjamin Netanyahu. “This substantial prize will be awarded, directly and securely, to any individual or group bold enough to show true action against tyranny,” the hackers’ statement read, along with an invitation to any would-be assassins to reach out via the encrypted messaging app Session. “All our communication and payment channels utilize the latest encryption and anonymization technologies, your safety and confidentiality are fully guaranteed.”
That bounty, Handala explained, was posted in answer to a statement about Handala published on the US Department of Justice website last week that offered $10 million for information leading to the identity or location of anyone who carries out “malicious cyber activities against US critical infrastructure” on behalf of a foreign government.
“Our message is clear: If you truly have the will and the power, come and find us!” Handala wrote in its response. “We fear no challenge and are prepared to respond to every attack with even greater force.”
In yet another post on its website this week, Handala also claimed to have doxed 28 engineers at military contractor Lockheed Martin working in Israel and threatened them with personal harm if they didn’t leave the country within 48 hours. When WIRED tried calling the phone numbers included in Handala’s leaked data, however, most of them didn’t work.
Apple says no device with its Lockdown Mode security feature enabled has ever been successfully compromised by mercenary spyware in the nearly four years since its launch. Amnesty International’s security lab head, Donncha Ó Cearbhaill, also says his team has seen no evidence of a successful attack against a Lockdown Mode–enabled iPhone. And Citizen Lab, which has documented several successful spyware attacks against iPhones, says none involve a Lockdown Mode bypass, while in two cases its researchers found the feature actively blocked attacks against NSO Group’s Pegasus and Intellexa’s Predator. Google researchers, meanwhile, found one spyware strain that simply abandons infection attempts when it detects the feature is enabled.
Lockdown Mode works by disabling commonly exploited iPhone features, such as most message attachment types and features like links and link previews. Incoming FaceTime calls are blocked unless the user has previously called that person within the past 30 days. When the iPhone is locked, it blocks connections with computers and accessories. The device will not automatically join nonsecure Wi-Fi networks, and 2G and 3G support is disabled. Apple has also doubled bounties for researchers who detect any Lockdown Mode bypass, with payouts up to $2 million.
Tech
This Premium Sennheiser Soundbar Is $1,000 Off
Looking for an all-in-one soundbar that sounds as big as it looks? Sennheiser’s Ambeo Max uses its oversized body to produce beefy, enveloping sound, and right now you can grab it for just $2,000 at Best Buy, a sizable $1,000 markdown from the usual list price. It’s one of our favorite standalone premium soundbars, particularly if you don’t want to deal with an exterior subwoofer but still want bigger bass than you’re likely to find on smaller options.
While it might be a bit larger than your average soundbar, Sennheiser uses the space well, packing a ton of functionality and drivers into the less-than-compact body. There are both full-range and 1-inch tweeters combined in every conceivable direction, and the result is an impressive reproduction of true spatial audio, something few other standalone bars can claim. As a result, it also has an impressive low-end, with bass that doesn’t rival dedicated subwoofers, but comes really close for how much simpler the setup process will be.
The larger footprint also allows for a huge number of inputs, more than you’re likely to find on those tiny soundbars that slide under your screen. In addition to an HDMI 2.1 output with eARC, you’ll get three HDMI inputs with 4K pass-through at 60Hz, USB, Ethernet, and optical audio. There are even RCA ports in case you want to hook this up to your turntable. There’s also a dedicated subwoofer output, in case you decide you want to add one to your setup down the road, giving you a ton of options should you decide to put the Ambeo Max at the center of your home audio setup.
Ready to make the move to a bigger, better soundbar? Swing on over to Best Buy to grab this hefty discount on the Sennheiser Ambeo Max, or check out our guide to the best premium soundbars for some of our other favorite picks. If you’re just out looking for a great deal in general, the Amazon Big Spring Sale is underway, and we’ve got a dedicated post with all the best discounts on everything from smartwatches to water bottles.
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