Entertainment
FDA recalls ‘Prazosin Hydrochloride’ blood pressure medication over cancer risk
U.S. Food and Drug Administration (FDA) has declared more than 580,000 bottles of a common blood pressure medication have been pulled from the market due to contamination with a potentially cancer-causing chemical.
The recall includes various strengths of “Prazosin Hydrochloride” capsules. The drug is commonly used to treat high blood pressure and prostate conditions, which is also sometimes prescribed off-label for PTSD related nightmares.
New Jersey based Teva Pharmaceuticals USA initiated the recall earlier this month. On October 24, FDA classified it as a Class II recall.
Why Prazosin Hydrochloride was recalled
As mentioned in the enforcement report of FDA, the testing of the medication revealed that the capsules contained elevated levels of an impurity known as “N-nitroso prazosin.”
The chemical structure is R2N−N=O, where R is usually an alkyl group. Nitrosamines have a nitroso group (NO+) that are “probable human carcinogens,” bonded to a deprotonated amine. Most nitrosamines are carcinogenic in animals.
Their possibility of formation can be during the manufacturing process or during storage.
FDA explained that exposure to this chemical “may cause temporary or medically reversible adverse health consequences or where the probability of serious health consequences is remote.”
Which medications are affected?
The recall spans three different dosage strengths of Prazosin Hydrochloride capsules that were distributed nationwide. The affected products are:
- 181,658 bottles of 1 mg capsules with lot numbers 3010544A and 3010545A, expiring in October 2025.
- 291,512 bottles of 2mg capsules across multiple lot numbers, with expiration dates from October 2025 through July 2026.
- 107,673 bottles of 5 mg capsules across multiple expiry dates extending into 2026.
What patients should do
Patients should not abruptly stop their medication as it can pose serious health threats. FDA recommends patients to take following steps:
- Immediately consult your doctor to get to know if your specification medication is part of recalled lots.
- Ask your doctor about any safer alternative option.
- Discontinue medicine under direct supervision of a healthcare professional
Other common medications like Zantac have also been recalled due to nitrosamine impurities in the past.
Ana de Armas and Tom Cruise’s upcoming movie Deeper is facing an unexpected delay amid the pair’s breakup.
The Mission Impossible star and the Ballerina actress parted ways weeks ago after nine months of their reported romance, and fans might not see the pair on the big screen, despite rehearsals already taking place in London.
According to internet personality Daniel Richtman, the production of the project has been put on hold after the film industry faced tariffs by US President Donald Trump, via Daily Mail.
It is pertinent to mention that Trump recently announced that any movie filmed outside of US will be charged a 100 per cent tariff.
Deeper tells the story of an astronaut on a voyage to explore the ocean.
Moreover, a source told US Weekly on October 30 that Ana and Tom’s romance first began after they “spent every day together” while “training for the intense underwater sequences” for their thriller.
“It started as a deep professional respect and then it ignited. Tom was completely captivated by Ana,” the insider added.
Sharing insights into their split, the tattler told the publisher that it was “Ana’s decision” to part ways as “she started to get a little uncomfortable with how fast” things were going between her and Tom.
However, the two “have a connection” and “they will see how things go in the future.”
KARACHI: The Sindh High Court (SHC) has issued notices to the Attorney General of Pakistan and other respondents over a petition challenging the 40% tax on sanitary napkins.
A two-member bench, comprising Justice Adnan Iqbal Chaudhry and Justice Jafar Raza, heard the petition filed by Alisha Shabbir and directed all parties to submit their responses within two weeks.
The petitioner argued that the government’s heavy taxation on raw materials for sanitary napkins has made them unaffordable for millions of women and girls.
She contended that under Articles 9 and 14 of the Constitution, every citizen has the right to health and life.
The petition seeks the inclusion of sanitary napkins as essential items and requests exemption from the Sales Tax Act 1990.
It also proposes that raw materials for sanitary napkins be placed under the Eighth Schedule to ensure that tax relief benefits reach consumers effectively.
The petitioner further highlighted that classifying sanitary napkins as “non-essential” and taxing them heavily constitutes a violation of fundamental rights.
The court accepted the plea for notice and fixed a two-week period for replies from the respondents and the Attorney General.
Robert Irwin receives “in-depth feedback” from Russell Crowe after each performance of his on Dancing with the Stars.
The 21-year-old Australian conservationist and TV personality attended the red-carpet premiere of Crowe’s new film, Nuremberg, where he conversed with Access Hollywood.
Irwin told the outlet that his long-time family friend, Crowe, a renowned actor and filmmaker, gives him feedback after each episode of Dancing with the Stars.
He said of the Gladiator star, “I’m incredibly grateful for his support on this dancing journey. It’s actually been really cool because Russell will message after [each] performance.”
Crowe does not say “this was a really great dance;” rather, he really delves into “the detail of, ‘Okay these steps were great, love the lines, love the clarity in the storytelling.’ To really get that very in-depth feedback is amazing, and it means a lot,” Irwin shared.
Moving forward, the Wild Times star and the son of famed zookeeper and television personality Steve Irwin mentioned why he cherishes Crowe’s constructive criticism.
“What I’m doing — I’m not a dancer, I’m trying to tell my story through dance, I’m trying to spread my message of positivity and passion and enthusiasm through dance, and Russell being there to support that means a lot,” Irwin explained.
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