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FDA recalls ‘Prazosin Hydrochloride’ blood pressure medication over cancer risk

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FDA recalls ‘Prazosin Hydrochloride’ blood pressure medication over cancer risk


 FDA recalls ‘Prazosin Hydrochloride’ blood pressure medication over cancer risk

U.S. Food and Drug Administration (FDA) has declared more than 580,000 bottles of a common blood pressure medication have been pulled from the market due to contamination with a potentially cancer-causing chemical.

The recall includes various strengths of “Prazosin Hydrochloride” capsules. The drug is commonly used to treat high blood pressure and prostate conditions, which is also sometimes prescribed off-label for PTSD related nightmares.

New Jersey based Teva Pharmaceuticals USA initiated the recall earlier this month. On October 24, FDA classified it as a Class II recall.

Why Prazosin Hydrochloride was recalled

As mentioned in the enforcement report of FDA, the testing of the medication revealed that the capsules contained elevated levels of an impurity known as “N-nitroso prazosin.”

The chemical structure is R2N−N=O, where R is usually an alkyl group. Nitrosamines have a nitroso group (NO+) that are “probable human carcinogens,” bonded to a deprotonated amine. Most nitrosamines are carcinogenic in animals.

Their possibility of formation can be during the manufacturing process or during storage.

FDA explained that exposure to this chemical “may cause temporary or medically reversible adverse health consequences or where the probability of serious health consequences is remote.”

Which medications are affected?

The recall spans three different dosage strengths of Prazosin Hydrochloride capsules that were distributed nationwide. The affected products are:

  • 181,658 bottles of 1 mg capsules with lot numbers 3010544A and 3010545A, expiring in October 2025.
  • 291,512 bottles of 2mg capsules across multiple lot numbers, with expiration dates from October 2025 through July 2026.
  • 107,673 bottles of 5 mg capsules across multiple expiry dates extending into 2026. 

What patients should do

Patients should not abruptly stop their medication as it can pose serious health threats. FDA recommends patients to take following steps:

  • Immediately consult your doctor to get to know if your specification medication is part of recalled lots.
  • Ask your doctor about any safer alternative option.
  • Discontinue medicine under direct supervision of a healthcare professional

Other common medications like Zantac have also been recalled due to nitrosamine impurities in the past. 





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WhatsApp to let users generate private summaries of unread chats

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WhatsApp to let users generate private summaries of unread chats


Silhouettes of laptop and mobile device users are seen next to a screen projection of Whatsapp. — Reuters/File

Meta-owned WhatsApp is working on a new feature that uses artificial intelligence (AI) to summarise unread messages, so users don’t have to scroll through endless group chats and one-on-one conversations.

The Meta-owned messaging and video calling platform said that it announced a feature that lets users summarise multiple unread chats.

This feature will allow users to catch up on multiple conversations more efficiently without opening them separately, it added. 

WhatsApp to let users generate private summaries of unread chats

According to WABetaInfo, chats will be summarised by the artificial intelligence. It emphasised that the process is secure, and messages will remain private through private processing. This means that Meta can not access the messages during the process.

Once development is complete, the feature will be rolled out to select beta testers.





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Here’s full list of airlines hit by cancellations, reroutes, delays

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Here’s full list of airlines hit by cancellations, reroutes, delays


US airports flight disruption top 4,200: Here’s full list of airlines hit by cancellations, reroutes, delays 

America’s aviation has been hit by catastrophic conditions on Tuesday, April 21, as three simultaneous crises hit the nation.

The primary reasons for the collapse include TSA staffing collapse, Iran-war fuel shock, and weather restrictions.

As per live FlightAware data, total delays worldwide reached 8,845 on Tuesday, with 675 delays occurring within, into, or out of the United States.

The total number of cancellations worldwide was 421, of which 28 occurred in or affected flights departing from US airports.

San Francisco International Airport became the epicenter of the disaster, with 475 delays and 69 cancellations following the FAA’s issuance of weather-related flight restrictions. Hartsfield-Jackson Atlanta, Boston Logan, and JFK International were the next most affected airports.

Full list of airlines with cancellations and delays

Major affected carriers include:

  • SkyWest (7 cancellations, 68 delays)
  • United Airlines (7 cancellations, 33 delays)
  • Southwest (2 cancellations, 71 delays)
  • Delta Airlines (1 cancellation, 51 delays)
  • American Airlines

International carriers operating US routes suffered heavily, including:

  • Japan Airlines (65 cancellations, 257 delays)
  • Air China (24 cancellations, 174 delays)
  • China Eastern (19 cancellations, 329 delays)
  • Emirates (2 cancellations, 25 delays)
  • Air Canada (7 cancellations, 21 delays)

Reroutes and fuel-driven cuts

Apart from delays and cancellations, airlines have been actively cutting down their schedules. 

United Airlines has reduced 5% of its schedule over six months. Air Canada plans to discontinue its JFK services for six months, starting June 1 and ending October 25. Delta Airlines lost an additional $400 million on fuel costs in March alone.

There are just 60 days left until the start of the FIFA World Cup, and the TSA training cycle takes four to six months.





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Jennifer Lopez and Will Smith viral dating claims raise big questions

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Jennifer Lopez and Will Smith viral dating claims raise big questions


Jennifer Lopez and Will Smith viral dating claims raise big questions

Jennifer Lopez and Will Smith are once again being linked together online, with many people wondering if something is going on between them.

The rumours have picked up quickly but there is no real proof that the two are dating.

The viral buzz started after old videos and past gossip started circulating again on social media.

As these clips made their way back into the spotlight, some fans started connecting dots and assuming that there might be a hidden story behind it.

But so far, nothing new has actually come out to support those claims.

A lot of this opinion seems to be coming from older speculations that have been around for years, which often involving Jada Pinkett Smith and Sean Combs.

These stories, however, were never confirmed yet they keep returning every now and then.

Right now, Lopez is said to be focusing on her life and work after her high-profile split from Ben Affleck.

At the same time, Smith still shares a public bond with Jada, even though they have spoken about living separately. Moreover, they do have a past connection, as they once talked about working together on a film that never happened.

For now, it looks like this is more about old rumours coming back again rather than anything new actually happening.





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