Business
Eli Lilly blows past quarterly estimates, hikes outlook as Zepbound and Mounjaro sales skyrocket
Eli Lilly on Thursday reported first-quarter earnings and revenue that blew past estimates and hiked its full-year sales outlook by $2 billion, as demand for its blockbuster weight loss drug Zepbound and diabetes treatment Mounjaro spiked again.
The pharmaceutical giant now expects 2026 revenue to come in between $82 billion and $85 billion, up from previous guidance of $80 billion to $83 billion.
Lilly also projects its full-year adjusted profit to be between $35.50 to $37 per share. That compares with a previous outlook of $33.50 to $35 per share.
Resilient demand for Zepbound and Mounjaro has helped fuel several strong quarters for Lilly despite lower prices for the medications in the U.S.
David Ricks, chief executive officer of Eli Lilly & Co., at the Semafor World Economy Summit during the International Monetary Fund (IMF) and World Bank Spring meetings in Washington, DC, US, on Friday, April 17, 2026.
Aaron Schwartz | Bloomberg | Getty Images
Mounjaro’s worldwide revenue rose 125% to $8.66 billion for the quarter, including U.S. sales of $4.2 billion. That surpassed the $7.26 billion in worldwide sales that analysts were expecting for the quarter, according to StreetAccount.
Zepbound, which entered the market roughly three years ago, posted $4.16 billion in U.S. revenue for the first quarter. That’s up 80% from the year-earlier period, as demand for the drug also rose while realized prices dropped. Analysts were expecting $4.04 billion in U.S. sales for Zepbound, according to StreetAccount.
Lilly is working to maintain its dominance in the booming market for GLP-1 drugs, with the company holding 60.1% share of the U.S. obesity and diabetes drug market in the first quarter, according to an earnings presentation. Novo Nordisk’s market share in the quarter was 39.4%.
Here’s what Eli Lilly reported for the first quarter compared with what Wall Street was expecting, based on a survey of analysts by LSEG:
- Earnings per share: $8.55 adjusted vs. $6.66 expected
- Revenue: $19.80 billion vs. $17.62 billion expected
Shares of Lilly rose more than 10% in afternoon trading Thursday.
The company posted first-quarter revenue of $19.80 billion, up 56% from the same period a year ago.
“Impressively, it’s like our fifth or sixth quarter in a row posting really strong topline growth numbers,” Lilly CEO Dave Ricks told CNBC in an exclusive interview Thursday. “That’s not usually something that pharmaceutical companies of our size do.”
Revenue in the U.S. climbed 43% to $12.1 billion. Eli Lilly said that was driven by a 49% increase in volume — or the number of prescriptions or units sold — for its products, primarily for Mounjaro and Zepbound. That was partially offset by lower realized prices of Zepbound and another medication for psoriatic arthritis and other conditions, the company said.
Notably, revenue outside the U.S. jumped 81% to $7.7 billion, propelled by a 95% surge in volume and partly offset by lower realized prices.
Ricks said Lilly had slowed down introductions in global markets when it experienced supply constraints in late 2024. But he said now Lilly is hitting its third or fourth quarter in the major markets across Europe, China and Brazil, where many patients are paying out of pocket.
“As those launches hit stride, you’re seeing the depth and breadth of the consumer market here,” Ricks said, referring to international markets.
The pharmaceutical giant booked net income of $7.40 billion, or $8.26 per share, for the first quarter. That compares with net income of $2.76 billion, or $3.06 per share, a year earlier.
Excluding one-time items associated with the value of intangible assets and other adjustments, Eli Lilly posted earnings of $8.55 per share for the first quarter.
The company’s newly approved GLP-1 pill for obesity, Foundayo, launched in the second quarter, so its sales are not included in Thursday’s report.
Still, the pill’s rollout is likely to dominate the discussion during Lilly’s first-quarter earnings call. Executives will likely face questions about whether Foundayo can reach the same level of momentum as the rival Wegovy pill from Novo Nordisk, which benefited from a three-month head start in the U.S.
In his interview with CNBC on Thursday, Ricks said more than 20,000 people have started taking Foundayo in its first few weeks on the market. More than 1,000 people a day are starting the drug, he added.
He said 80% of patients taking the drug are new to taking GLP-1s.
Ricks added that the company needs to build consumer awareness around Foundayo, noting that the company has not advertised it on TV.
“So what we’re seeing now is basically organic demand, which is really strong to us,” Ricks said.
In February, Lilly said it expects to benefit from Foundayo’s launch, Medicare coverage of obesity drugs coming online later this year, and continued worldwide demand for Mounjaro and Zepbound. But the company also expects to face pricing pressure, driven by a drug pricing deal with President Donald Trump and lower cash-pay prices for Zepbound, among other factors.
Still, Ricks said in an interview in late April that he expects lower prices to accelerate prescription volumes in the U.S. He also estimated that global GLP-1 use will rise from approximately 20 million patients at the end of last year to 30 million at the end of 2026.
— CNBC’s Angelica Peebles contributed to this report.
Correction: Lilly posted first-quarter revenue of $19.80 billion, up 56% from the same period a year ago. An earlier version misstated the time frame.
Spirit Airlines check-in Kiosks sit idle at Oakland International Airport on August 13, 2025 in Oakland, California.
Justin Sullivan | Getty Images
Spirit Airlines could shut down as early as 3 a.m. ET Saturday, according to people familiar with the matter. The carrier has failed to secure a financial lifeline to continue operating, though it hasn’t commented on the potential shutdown or its plans.
About 290 Spirit flights are scheduled for Saturday, according to aviation site Flightradar24. Another 381 are scheduled for Sunday.
Travelers with Spirit tickets could be understandably rattled. While there have been some U.S. airlines to shut down in recent years, the budget carrier is larger than most recent airline failures and links major cities like New York, Miami, Detroit and Los Angles — and many others in between — with its Airbus jets.
Here’s what travelers need to know:
You have a Spirit ticket. What should you do?
Immediately? Nothing.
Travelers who are booked on a Spirit flight, like this CNBC reporter is for later this month, are likely to receive a refund if they purchased tickets with a credit card.
If the ticket was bought with a debit card or with loyalty points, however, the chances of recovering funds are slim to none, said Henry Harteveldt, founder of Atmosphere Research Group, a travel consulting firm.
“If you’re holding a reservation for a flight on Spirit don’t proactively cancel it. Wait for the airline to announce it is shutting down,” he said.
Would Spirit be able to help you at the airport?
Don’t count on it.
Spirit has declined to comment on a potential shutdown. If it confirms an end to operations, the carrier will most likely have information on its website about travelers’ next steps.
Harteveldt said travelers shouldn’t go to the airport expecting to find Spirit staff in the event the airline ceases operations. Call centers are likely to be overwhelmed if they are still staffed.
That could leave passengers with fewer answers than they’d like, but other airlines are likely to help assist affected customers.
Airlines that offer last-minute fares, likely with some discounts, will be available to travelers at airport ticket counters.
How can another airline help?
United Airlines, JetBlue Airways, Frontier Airlines and American Airlines are among the carriers that have said they are ready to assist Spirit customers and crews if the carrier shuts down.
That could mean scheduling additional flights to carry the stranded passengers, similar to what they do during a hurricane or other natural disaster.
Why could Spirit shut down?
Spirit, known for bright yellow planes, low fares and fees for everything else, had been successful for years, but this week it’s been on the brink of liquidation after failing to reach a deal with bondholders for a $500 million government bailout from the Trump administration.
Last year Spirit filed for its second bankruptcy in less than a year, though it’s had a host of problems even before then.
A plan to be acquired by JetBlue was blocked. Rising costs upended its business model. An engine defect grounded dozens of its planes. And, more broadly, upscale travel became more popular with consumers, driving airline profits.
At the same time, big, legacy airlines were selling their own basic economy fares that were similar to what Spirit was offering, but with bigger networks.
What does this mean for travel going forward?
Airlines have been adding flights since Spirit’s bankruptcy filing last year on some of its routes and at major airports. They’re likely to keep doing so.
Experts have said they expect fares to rise, at least in some markets, if the discounter goes away, even though the carrier has shrunk substantially.
Business
Middle East crisis: Air India to make food optional, help cut price of tickets – The Times of India
NEW DELHI: Desperate times call for desperate measures. Full service Air India is planning to make meals optional on its domestic and short international (under two hour) flights. Once this “unbundling” rolls out in the next month or two, passengers opting out of meals could have upwards of Rs 250 shaved off their ticket price. While this move, say people in the know, is “on the anvil,” the airline is looking at several other unprecedented measures to fly through the severe cost-revenue turbulence caused by the unending West Asia war.While not opting for meals could lead to slightly cheaper economy tickets, AI is looking at unbundling lounge access for business class passengers because those opting out of this, could get their tickets cheaper. On an average, lounge operators charge Rs 1,100-1,400 per user at metro airports and Rs 600-700 at non metros.The average spend is about Rs 1,000 per lounge. Many business class flyers are frequent travellers who just make it to airports in time for their flight and do not head to the lounge. If unbundled, this could be a saving in their ticket cost. Banks have been reducing lounge access for credit card users for the same reason to cut their costs.“From Day One, Air India has had meals bundled in its ticket price. Now the way aviation turbine fuel (ATF) price is rising and the rupee crashing since Feb 28, ticket prices are going up. India is a price-sensitive market and raising fares beyond a point leads to a fall in traffic with many opting to travel by train or road. This has led to the rethinking to unbundle meals on some flights. Other steps are also being considered,” said people in the know.Several airlines globally have over the past few years unbundled their onboard offerings. Many international full service airlines offer a basic meal in economy while giving the option of buying gourmet meals at an additional cost. Ditto for alcoholic beverages, with cheaper beer and wines being given at no extra cost while the others being charged for. “For passengers, the distinction between full service and low cost airlines is blurring very fast,” said an industry old-timer.
A tree surgeon said he thought he “was going to die” when he suffered a powerful electric shock from an overhead line while clearing hedges in Wiltshire.
Joshua Pocknell was working just after midnight on the A3102 near Royal Wootton Bassett when the mobile lighting tower he was pushing touched an 11,000 volt overhead powerline.
The 26-year-old was seriously injured and taken to hospital, where he spent the next five weeks, workplace watchdog the Health and Safety Executive (HSE) said.
“My whole body locked and I felt hot and cramping,” Mr Pocknell said of the shock.
“I could hear the electricity in my head and thought I was going to die.
“I hit the floor and passed out, still cramping.
“I later discovered a hole had burnt through my arm and hip all the way to the bone.”
More than two years after the incident on January 19 2024, the tree surgeon said he still experiences “considerable pain”.
“My injuries were complex and challenging and there were five or six different surgeons involved in my treatment,” he said.
“I still experience considerable pain and strange bodily sensations, including nerve pain and itching.
“This incident has torn the life from beneath me and I don’t think I will be able to return to the job that I used to love.”
The regulator said it investigated the incident and found Mr Pocknell’s employer, Upton Specialised Tree Services, did not properly plan for or risk assess the dangers posed by overhead power lines.
The firm did not put up barriers or provide training in operating the mobile lighting tower.
Upton Specialised Tree Services pleaded guilty to the charge of breaching Regulation 14 of the Electricity at Work Regulations 1989 by virtue of Regulation 3, the HSE said, and was fined £60,000 and ordered to pay £6,237 in costs at Bristol Magistrates’ Court on Friday.
HSE inspector Tom Preston said: “Joshua is lucky to be alive.
“Overhead electrical power lines present extreme risks to workers, but the risks can and must be controlled.
“Work near overhead power lines should only be carried out where it can be done safely, following a suitable risk assessment, the use of barriers or safety zones, and proper training on the equipment being used.
“In this case, a worker sustained severe injuries in a traumatic incident for all concerned that was entirely preventable.
“HSE will take action against those who fail to take the steps necessary to protect people at work.”
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