Business
Novo Nordisk cuts sales and profits guidance amid obesity drug competition
The drugmaker behind Ozempic and Wegovy has cut its sales and profit targets in the face of intense competition from other weight-loss and diabetes treatments.
Novo Nordisk warned over weaker-than-expected profits amid the recent growth of US rival Eli Lilly’s Mounjaro and Zepbound injection treatments.
The boss of the Danish pharmaceutical firm linked its reduced guidance to the market for weight-loss treatments being “more competitive than ever”.
Mike Doustdar, chief executive of Novo Nordisk, said: “While we delivered robust sales growth in the first nine months of 2025, the lower growth expectations for our GLP-1 treatments, for diabetes and obesity, have led to a narrowing of our guidance.”
The firm said sales are set to rise by up to 11% this year. It had previously guided towards growth of up to 14%.
It also reported that operating profits will rise by up to 7% this year, pulling down its previous guidance of up to 10%.
It came as the business reported that sales in its diabetes and obesity care division grew by 12% in Danish kroner, or 15% at constant currency rates, over the first nine months of 2025.
This included a stronger performance across obesity, with 7% growth in the diabetes-focused part of the division, which includes Ozempic.
Meanwhile, operating profits grew by 5%, or 10% at constant currency rates, for the year so far.
It said this included a nine billion kroner (£6.7 billion) impact from one of restructuring costs.
This came after the company launched a major overhaul in September, which included plans to cut around 9,000 jobs globally.
Mr Doustdar added: “Our company-wide transformation has already driven operational efficiencies, and we have a renewed focus that can deliver a range of potential treatment options that will serve millions more patients, mainly in obesity.
“We aim to accelerate on all fronts to be able to compete better in dynamic and increasingly competitive markets.”
Business
Stellantis CEO says automaker is stronger together as stock plummets amid $26 billion charge
Stellantis CEO Antonio Filosa speaks during an event in Turin, Italy, Nov. 25, 2025.
Daniele Mascolo | Reuters
DETROIT — Stellantis CEO Antonio Filosa on Friday said the automaker plans to move forward as one company amid speculation that it would be better off selling brands or splitting up after disappointing results.
“Stellantis is a very strong global company that is very proud to have very deep regional groups,” Filosa, an Italian native, told reporters during a media call. “It makes all of sense to stay together. We want to stay together for many years to come.”
His comments come hours after the company announced 22 billion euros ($26 billion) in charges from a business restructuring that includes pulling back on electrification plans and reintroducing V8 engines to U.S. models.
Filosa described the actions as an “important strategic reset of our business model, with the only intention to put our customer preferences back at the center of what we do globally and in each regions.” He said the “mission is to grow” after notable declines in market share in recent years.
Stellantis’ stock plunged more than 25% in trading in Milan and was down 23% on Wall Street.
Filosa on Friday did not specifically rule out the possibility of regionally refocusing or shrinking the company’s vast portfolio of 14 auto brands that includes U.S. brands Jeep, Ram and Chrysler, as well as Italian nameplates Fiat and Alfa Romeo, which have not performed well domestically.
Stellantis-listed shared in Milan and New York
“We want to really manage our brands in the sense to provide to them the products and the technology that our customers, that are now at the center of our strategic reset, will tell us that they want and they need,” he said. “This is our core mission.”
Filosa said additional information about the company’s plans moving forward will come at a May 21 investor day.
Friday’s announcement comes days after Stellantis executives met with the company’s U.S. franchised dealers at their annual National Automobile Dealers Association conference with a message that the automaker planned to grow sales across its U.S. lineup of brands, according to two dealers who attended the meeting.
$26 billion in charges
The majority of Friday’s announced charges — 14.7 billion euros — are related to realigning product plans with consumer preferences and new emission regulations in the U.S.
Other charges include 2.1 billion euros in resizing the company’s EV supply chain, 4.1 billion euros in warranty costs and 1.3 billion euros in restructuring European operations.
The automaker also canceled its dividend for 2026 and issued a 5 billion euro nonconvertible hybrid bond.
2026 Jeep Grand Wagoneer
Jeep
The charges related to EVs follow General Motors and Ford Motor announcing billions of dollars in similar expenses due to pullbacks in plans for all-electric vehicles.
Shares of Ford and GM were not as impacted as much as Stellantis, which also issued lower-than-expected guidance amid years of strategic problems with the company.
Stellantis said it anticipates a net loss for 2025. For 2026, the auto giant is targeting a mid-single-digit percentage increase in net revenue and a low-single-digit rise in its adjusted operating income margin.
“While charges were expected, the amount comes in above F ($19.5B) and GM ($7.6B). Expect shares to trade meaningfully lower today as a result. We continue to believe STLAM is a show-me-story. In the US, the company has lost substantial market share given high pricing and a perceived lack of product investment,” RBC Capital Markets analyst Tom Narayan said in a Friday investor note.
Past mistakes
Filosa on Friday called out mistakes by former company leaders more than he has since he succeeded Carlos Tavares as CEO in June.
Tavares, who was ousted in December 2024 amid disagreements with the Stellantis board, in a book last year reportedly said that the group’s French, Italian and U.S. operations might have to be split amid pressure from its main stakeholders.
It’s been just over five years since Stellantis was created through a $52 billion combination of Italian American automaker Fiat Chrysler and France-based Groupe PSA on Jan. 16, 2021.

The merger formed the fourth-largest automaker by volume, but the company has run into significant problems in recent years amid its investments in all-electric vehicles, focus on profits over market share and cost-cutting efforts to the detriment of products.
Stellantis’ global sales under Tavares fell 12.3% from 6.5 million in 2021 — the year the company was formed — to 5.7 million in 2024. That included a roughly 27% collapse in the U.S. in that period to 1.3 million vehicles sold. The automaker dropped from fourth in U.S. sales to sixth, declining from an 11.6% market share to 8% during that time frame.
Stellantis’ global market share has fallen from 8.1% in 2020 to an estimated 6.1% last year, according to S&P Global Mobility.
Correction: Global market share for Stellantis has fallen from 8.1% in 2020 to an estimated 6.1% last year, according to S&P Global Mobility. An earlier version mischaracterized the percentage.
Business
FTSE 100 closes choppy week higher amid US rally
The FTSE 100 closed a volatile, and record-breaking, week on the front foot on Friday, recouping some of Thursday’s heavy falls.
The FTSE 100 Index closed up 60.53 points, 0.6%, at 10,369.74.
The FTSE 250 ended up 104.54 points, 0.5%, at 23,207.89, and the AIM All-Share advanced 3.90 points, 0.5%, at 806.80.
For the week, the FTSE 100 was up 1.4%, the FTSE 250 was down 0.2%, and the AIM All-Share declined 1.5%.
Despite the gains, data providers and software stocks in London ended a turbulent week with further losses amid fears of AI‑driven disruption, although US technology stocks rallied after Thursday’s slump.
Goldman Sachs explained the launch of a legal automation tool and a new large language model by US AI firm Anthropic, along with broad ramping of AI capacity and services, has led to a sharp rotation out of software and related sectors globally.
“Any company which collates, aggregates, disseminates software and data as a service are seen as increasingly vulnerable to disruption from AI-driven tools. The Anthropic announcement was just a catalyst to realise fears that have been growing,” Goldman said.
On the FTSE 100, Relx, which owns legal publisher LexisNexis, fell 4.6%, credit checking agency Experian declined 4.7%, accountancy software company Sage dipped 3.1% and financial data provider London Stock Exchange eased 1.1%.
On Relx, JPMorgan analyst Daniel Kerven attempted to placate investor fears.
“Relx is not a software business that is going to be eaten by AI,” he claimed.
“It is a data and analytics company. Its value is in owning, curating and licensing authoritative information, and applying technology to its data to provide analytics and models that help the decision making of its customers. Whether decisions are made by human professionals or automated AI workflows, Relx will remain the trusted source of the underlying data, content and analytics that those decisions depend on”, Mr Kerven wrote.
In European equities on Friday, the CAC 40 in Paris closed up 0.4%, while the DAX 40 in Frankfurt advanced 0.9%.
Stellantis plummeted 25% as it unveiled preliminary second-half figures showing a deep net loss, after the car maker took a heavy charge to scale back its push into electric vehicles, while also announcing the sale of its stake in a Canadian battery joint venture and suspending its dividend.
The Hoofddorp, Netherlands-based auto group said it expects a net loss of between 19 billion euros and 21 billion euros, widening from a 100 million euro loss, after recognising around 22 billion euros of charges.
The charges were largely driven by what Stellantis described as a “strategic shift” to better align its product plans with customer demand, including a slower-than-expected transition to battery electric vehicles.
UBS said “given the magnitude of the kitchen sinking and the soft 2026 guide, we would expect a negative initial share price reaction”.
But it said the “decisive cleaning up” of new management in combination with the operational turnaround in North America, supported by solid overall market fundamentals in the region, leaves Stellantis shares “attractive” on a US “comeback” case in the coming quarters.
But Citi said given the announcement does not include any factory closures “we do not think the news yet resets fully the cost base at Stellantis which is likely necessary on the reduced market shares. We think any upside to Stellantis most likely feature capacity reductions to fully reset the North America and European businesses”.
Stocks in New York rallied after Thursday’s heavy falls. The Dow Jones Industrial Average soared 1.8%, and the S&P 500 jumped 1.4%, as did the Nasdaq Composite.
Missing out on the rebound, Amazon plunged 8.0% after first-quarter guidance disappointed and the technology firm outlined plans for a significant ramp in capital expenditure in the coming year.
Chief executive Andy Jassy said the Bellevue, Washington-based technology company plans to invest 200 billion dollars in 2026, comfortably above FactSet consensus of 146.6 billion dollars, and around 52% ahead of 2025’s 131.8 billion dollars.
Mr Jassy told a conference call with investors the increased spend would “predominantly” go to Amazon Web Services (AWS), Amazon’s cloud computing business.
“We have very high demand, customers really want AWS for core and AI workloads and we’re monetising capacity as fast as we can install it,” he added.
The plans come a day after Google owner Alphabet said it will spend between 175 billion dollars and 185 billion dollars in 2026, while Facebook owner Meta Platforms recently said its capital expenditure could nearly double from 2025 to 115 billion dollars to 135 billion dollars.
Mr Jassy pointed out Amazon has “deep experience understanding demand signals” in the AWS business and then turning that capacity into a strong return on invested capital.
“We’re confident this will be the case here as well,” he added.
Analysts at Wedbush, who remain bullish on Amazon, think the increase in spending will remain an “overhang as investors digest the guide and will likely need to see more tangible returns before regaining comfort”.
The yield on the US 10-year Treasury was quoted at 4.22%, widened from 4.21%. The yield on the US 30-year Treasury was quoted at 4.87%, stretched from 4.86% on Thursday.
The pound was quoted higher at 1.3612 dollars at the time of the London equities close on Friday, compared with 1.3536 dollars on Thursday.
The euro stood higher at 1.1814 dollars, against 1.1791 dollars. Against the yen, the dollar was trading slightly higher at 157.04 yen compared with 156.96 yen.
Back in London, Metlen Energy & Metals sank 20% on the FTSE 100 after it revised down its earnings expectations for the full year, as it noted challenges with its M Power Projects business and the timing of transactions in its asset rotation plan of M Renewables.
Metlen is an Athens and London-based aluminium producer and electricity generator. It also invests in network infrastructure, battery storage, and other green technologies.
The company explained that further to the challenges noted in its interim report back in September, it has identified additional cost overruns and schedule delays solely impacting the performance of MPP.
Gold was quoted higher at 4,946.87 dollars an ounce on Friday, against 4,848.34 dollars at the same time on Thursday.
Brent oil was quoted at 68.47 dollars a barrel on Friday, up from 67.37 dollars late on Thursday.
The biggest risers on the FTSE 100 were Burberry Group, up 58p at 1,180p, International Consolidated Airlines, up 18.2p at 438.5p, Fresnillo, up 138p at 3,694p, Barclays, up 12.65p at 479.1p and Airtel Africa, up 7.4p at 327.6p.
The biggest fallers on the FTSE 100 were Metlen Energy & Metals, down 9.1p at 35.8p, Experian, down 122p at 2,499p, Relx, down 104p at 2,145p, Sage Group, down 26.8p at 844.4p and Compass Group, down 54p at 2,125p.
Next week’s global economic calendar has delayed US nonfarm payrolls and US inflation figures plus a GDP reading in the UK.
Monday’s UK corporate calendar has full-year results from Plus500 and Porvair.
Contributed by Alliance News
Business
US stocks today: Wall Street rebounds as tech equities recover, bitcoin steadies – The Times of India
US stock markets moved higher on Friday, clawing back part of the heavy losses seen earlier in the week, as technology shares recovered and bitcoin halted its recent slide. The rebound came after several volatile sessions driven by worries over massive spending on artificial intelligence and its impact on corporate profits.The S&P 500 rose 0.9 per cent, marking only its second gain in the past eight sessions. The Dow Jones Industrial Average jumped 776 points, or 1.6 per cent, while the Nasdaq Composite was up 0.5 per cent by mid-morning trading in New York.Chipmakers led the recovery. Nvidia climbed 4.9 per cent, trimming a weekly decline of more than 10 per cent, while Broadcom gained 3.8 per cent after falling sharply earlier in the week. According to news agency AP, hopes of strong long-term demand for chips linked to artificial intelligence continued to support the sector.
AI spending worries hit Amazon
Despite the broader rebound, concerns over soaring AI investment remained. Amazon shares slumped 8.5 per cent after the company said it expects to spend around $200 billion this year on areas such as AI, chips, robotics and low-earth-orbit satellites. Similar spending plans announced earlier by Alphabet have raised questions about whether such large investments will deliver enough future profits.As per news agency AFP, investors have grown cautious after a period when enthusiasm around AI lifted much of the technology sector. Chris Low of FHN Financial said markets were now reassessing whether the sell-off had gone too far, noting that traders felt some of the recent declines may have been “overdone”.Even with Friday’s gains, the S&P 500 was still on course for its third weekly fall in four weeks.
Bitcoin stabilises, crypto stocks jump
Bitcoin showed signs of stabilising after weeks of losses that wiped out more than half its value since its October peak. The cryptocurrency recovered to around $68,000 after briefly slipping near $60,000 late on Thursday.The move helped lift shares linked to the crypto sector. Robinhood Markets surged 11.7 per cent, Coinbase Global rose 7.3 per cent, and Strategy, a company known for holding large amounts of bitcoin, jumped 15.9 per cent.
Consumers, airlines and smaller stocks gain
US consumer sentiment also provided some support. A preliminary survey from the University of Michigan showed sentiment improving slightly, defying expectations of a fall. The improvement was strongest among households that own shares.Airline stocks gained on hopes that stronger confidence would translate into more travel spending. United Airlines rose 5.4 per cent, American Airlines gained 4.6 per cent, and Delta Air Lines added 4.4 per cent.Smaller companies outperformed larger peers, with the Russell 2000 index climbing 2.3 per cent. These firms tend to be more sensitive to the strength of the US economy.In the bond market, US Treasury yields were largely steady. The yield on the 10-year Treasury held at around 4.21 per cent, unchanged from late Thursday.
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