Business
Stocks up as Powell leaves door ajar for rate cut
The FTSE 100 posted another record closing peak on Friday as Jerome Powell said shifting economic risks may justify an interest rate cut in the US.
The FTSE 100 index closed up 12.20 points, 0.1%, at 9,321.40. It earlier traded as high as 9,357.51.
The FTSE 250 ended up 259.39 points, 1.2%, at 22,077.23 and the AIM All-Share finished 6.17 points higher, 0.8%, at 765.03.
For the week, the FTSE 100 rose 2.0%, the FTSE 250 advanced 1.5% and the AIM All-Share climbed 0.6%.
In a keenly awaited speech, Federal Reserve chairman Jerome Powell left the door open to an interest rate cut at its September meeting, noting a “shifting” balance of economic risks may warrant such a move.
Speaking at the Jackson Hole economic symposium, Mr Powell said: “The baseline outlook and the shifting balance of risks may warrant adjusting our policy stance.”
But he added “the stability of the unemployment rate and other labour market measures allow us to proceed carefully as we consider changes to our policy stance”.
Padhraic Garvey at ING commented: “Chair Powell could have been super balanced, or even hawkish. But he effectively chose to endorse the market discount for a rate-cutting phase ahead. It’s had quite the reaction. Risk assets are up, the dollar down.”
In New York, the Dow Jones Industrial Average soared 2.0%, as did the Nasdaq Composite, while the S&P 500 jumped 1.6%.
On the labour market, the Fed chairman said while it “appears to be in balance, it is a curious kind of balance that results from a marked slowing in both the supply of and demand for workers. This unusual situation suggests that downside risks to employment are rising”.
On tariffs, Mr Powell said a “reasonable base case” is that they create a “one-time” shift up in the price level, although he added those effects will take time to fully work their way into the economy.
“In the near-term, risks to inflation are tilted to the upside, and risks to employment to the downside – a challenging situation,” Mr Powell said.
“With policy in restrictive territory, the baseline outlook and the shifting balance of risks may warrant adjusting our policy stance,” he added.
While stocks rose, the dollar fell, while US bond yields declined.
The pound jumped to 1.3539 US dollars late on Friday in London, compared to 1.3426 US dollars at the equities close on Thursday.
The euro firmed to 1.1726 US dollars, higher against 1.1619 US dollars. Against the yen, the dollar was trading lower at 146.61 yen compared to 148.21 yen.
In Europe, the CAC 40 in Paris ended up 0.5%, while the DAX 40 in Frankfurt closed up 0.3%.
The yield on the US 10-year Treasury was at 4.26%, narrowed from 4.34%. The yield on the US 30-year Treasury was 4.87%, trimmed from 4.94%.
In London, trading recovered from a sluggish start supported by news that UK consumer confidence improved in August, boosted by the latest interest rate cut, although uncertainty over the possibility of future tax hikes and inflationary pressures weighed on expectations going forward.
The GfK consumer confidence index rose to minus 17 in August from minus 19 in July, above the FXStreet-cited consensus forecast of minus 20.
Consumer expectations for their personal financial situation over the next 12 months rose to plus 5 in August from plus 2 in July, while expectations for the general economic situation over the next 12 months declined to minus 30 from minus 29.
Neil Bellamy, consumer insights director at GfK, said: “The biggest changes in August are in confidence in personal finances, with the scores looking back and ahead a year each up by three points.
“This is likely due to the Bank of England’s August 7 cut in interest rates, delivering the lowest cost of borrowing for more than two years.”
AJ Bell investment analyst Dan Coatsworth said the slight uptick is “good news” for retailers, hospitality and travel businesses, but “no-one will be getting carried away given this is just a case of people feeling a bit less bad rather than genuinely optimistic about the economic outlook”.
On the FTSE 100, gains were broad-based with Asian-focused bank Standard Chartered leading the way, up 4.2%, while housebuilders Persimmon and Berkeley climbed 2.3% and 2.2% respectively, and British Airways owner, IAG, added 2.3%.
On the FTSE 250, WH Smith rallied 11%, recouping a small slice of Thursday’s dramatic 42% fall in the wake of lowered guidance after an accounting error.
Morgan Advanced Minerals rose 3.6% after Vesuvius agreed to buy its Molten Metal Systems business for a total enterprise value of £92.7 million.
In addition, the England-based manufacturer of carbon and ceramic materials, said it has instructed Investec Bank to launch the third tranche of its ongoing share buyback immediately upon completion of the second tranche.
Each tranche to date has been for up to £10 million, under a total buyback programme for up to £40 million.
Revolution Beauty leapt 20% as it announced the return of its co-founders to the business after terminating its formal sales process.
The news came as the firm pledged to slash costs amid declining sales and profitability, and raised £15 million via a placing and subscription.
This includes cornerstone investment from the make-up brands co-founders, Tom Allsworth and Adam Minto, and from its largest shareholder, boohoo, now trading as Debenhams.
Between them the cornerstone investors hold just under 58% of Revolution Beauty stock, with boohoo having a 27% stake.
Mr Allsworth will step in as chief executive over the “coming days”, the firm said, with Colin Henry stepping down as interim chief executive at that point, while Mr Minto will also return to the business in a consulting capacity.
A barrel of Brent traded at 67.59 US dollars late Friday, up from 67.13 US dollars on Thursday. Gold pushed up to 3,375.22 US dollars an ounce against 3,343.46 US dollars.
The biggest risers on the FTSE 100 were Standard Chartered, up 57.0 pence at 1,417.0p, Persimmon, up 25.5p at 1,128.5p, International Consolidated Airlines, up 8.8p at 394.5p, Scottish Mortgage Trust, up 24.0p at 1,095.0p and Berkeley Group, up 80.0p at 3,792.0p.
The biggest fallers on the FTSE 100 were British American Tobacco, down 78.0p at 4,315.0p, Coca-Cola Europacific down 120.0 pence at 6,710.0p, Coca-Cola HBC, down 52.0p at 3,892.0p, Tesco, down 5.2p at 426.3p and National Grid, down 10.5p at 1,049.0p.
Financial markets in London are closed on Monday for the August bank holiday.
Later in the week results are due from insurer Prudential and sports retailer JD Sports Fashion.
The global economic calendar on Monday has the German ifo business climate report and US new home sales figures.
Contributed by Alliance News.
Business
FDA official calls UniQure’s gene therapy a ‘failed’ treatment for Huntington’s disease
Thomas Fuller | SOPA Images | Lightrocket | Getty Images
UniQure needs to run another study to prove that its gene therapy “actually helps people with Huntington’s disease,” a senior U.S. Food and Drug Administration official said on a call with reporters Thursday.
The official, who requested anonymity before discussing sensitive information, confirmed the agency has asked the company to run a placebo controlled trial of its treatment, which is administered directly into the brain. UniQure has said that type of study isn’t ethical because it would require putting people under general anesthesia for hours, a characterization the official disputed.
“So what is really going on? UniQure is the latest company to make a failed therapy for Huntington’s patients,” the official said. “They likely acknowledge or understand at some deep level that their trial failed years ago, and instead of doing the right thing and running the correct clinical study, UniQure is performing a distorted or manipulated comparison in the mind of FDA.”
The comments mark the latest development in a messy public spat between UniQure and the FDA, and as the agency comes under fire for a number of recent drug approval application rejections, including some where companies have accused it of going back on previous guidance. FDA Commissioner Marty Makary in an interview with CNBC’s Becky Quick last week seemingly criticized UniQure’s gene therapy for Huntington’s disease. Makary didn’t name UniQure but described its treatment.
UniQure then accused the FDA of reversing its stance that the company’s clinical trial data would be sufficient to seek approval. UniQure’s study used an outside database to measure how patients with Huntington’s disease might decline without treatment, known as an external control. UniQure has said it wouldn’t be feasible to run a true randomized, double-blind placebo-controlled study, considered the gold standard, because it wouldn’t be ethical to make people undergo a sham hours-long brain surgery.
The FDA official said the agency “never agreed to accept this distorted comparison” and the FDA “never makes such assurances.” Instead, the “FDA will always say, ‘Well, we have to see the data when we get it.'”
UniQure didn’t immediately comment.
The company’s stock rose more than 10% on Thursday and has fallen 58% this year as of Thursday afternoon.
Business
US mortgage rates rise to 6% after three-week slide as oil-driven bond yields climb – The Times of India
The average long-term US mortgage rate edged higher this week, ending a three-week decline as bond yields rose amid oil-price pressures linked to the war with Iran.The benchmark 30-year fixed mortgage rate increased to 6% from 5.98% last week, mortgage buyer Freddie Mac said on Thursday. A year ago, the average rate stood at 6.63%, AP reported.The modest uptick breaks a three-week slide in borrowing costs, with mortgage rates having hovered close to the 6% mark for most of this year. Last week’s average had marked the first time the rate dipped below 6% since September 2022, reaching its lowest level in nearly three and a half years.Mortgage rates are influenced by several factors, including the Federal Reserve’s interest-rate policy, investor expectations about inflation and economic growth, and movements in the bond market.They typically track the direction of the 10-year US Treasury yield, which lenders use as a benchmark for pricing home loans.The 10-year Treasury yield rose to 4.14% at midday Thursday, up from around 4% a week earlier.Treasury yields have moved higher in recent days as rising oil prices added fresh inflation concerns, potentially complicating the Federal Reserve’s plans to cut interest rates.
Business
US stocks today: Dow tumbles 800 points, S&P 500 and Nasdaq slip as oil surges after Iran tanker strike – The Times of India
US stock markets fell on Thursday as investors turned cautious after the previous session’s rally, while rising oil prices and geopolitical tensions weighed on sentiment.The Dow Jones Industrial Average dropped 801 points, or 1.6 per cent, dragged down by losses in stocks such as Caterpillar and Goldman Sachs. The S&P 500 declined 0.9 per cent, while the Nasdaq Composite fell 0.6 per cent.The selloff came as crude oil prices jumped to their highest level since June 2025 after Iran said it had struck an oil tanker with a missile. US West Texas Intermediate crude futures surged 6 per cent to trade above $79 per barrel, while international benchmark Brent crude futures rose about 3 per cent to more than $84 per barrel. Oil prices had stabilised in the previous trading session.Markets had rallied on Wednesday, supported by gains in technology and semiconductor stocks. The Dow had snapped a three-day losing streak, while the S&P 500 and Nasdaq Composite ended the session with solid gains.Despite the ongoing US-Israeli air campaign against Iran, US markets have performed relatively better than European and Asian counterparts this week, largely supported by a rebound in technology stocks that had been hit hard during February’s selloff.The tech-led recovery in the previous session helped the Nasdaq erase its weekly losses, putting the index on track to end the week in positive territory if gains hold through Friday.Investors remain concerned that prolonged disruption to shipping through the Strait of Hormuz — a key global energy corridor –could push oil prices higher and add to inflationary pressures through rising energy and shipping costs.Markets are particularly wary of crude prices moving towards $100 per barrel, which could complicate the Federal Reserve’s efforts to control inflation while considering interest-rate cuts.“For the past couple of years, bringing inflation down has been the Fed’s entire focus, and they were finally making progress. But if energy stays expensive, inflation could start climbing again and that would force the Fed to rethink its plans,” said Adam Sarhan, chief executive of 50 Park Investments, Reuters quoted.According to data compiled by LSEG, investors are increasingly expecting the Federal Reserve to delay a 25-basis-point interest rate cut to September from the previously anticipated July timeline.Among sectors, healthcare led declines on the S&P 500, dropping 1.6 per cent. The energy index, however, gained 0.7 per cent, with shares of ConocoPhillips and Valero Energy rising about 2 per cent each.The CBOE volatility index (VIX), widely seen as a gauge of market fear, rose 0.9 points to 22.08, reflecting cautious investor sentiment. The small-cap Russell 2000 index fell 1 per cent.Travel and tourism stocks, which are sensitive to fuel costs, were under pressure. Delta Air Lines slipped 3.3 per cent, while Royal Caribbean Cruises declined 0.6 per cent.On the other hand, some travel booking companies rallied sharply. Booking Holdings jumped 11 per cent and Expedia surged 8 per cent after a report by The Information said OpenAI was scaling back on-platform shopping checkout plans for ChatGPT, easing concerns about disruption to online marketplace businesses.Chip stocks showed mixed performance. Nvidia edged down 0.3 per cent, while Marvell Technology gained 1.3 per cent.Shares of Broadcom rose 2.9 per cent after the chip designer projected that its artificial intelligence chip revenue could exceed $100 billion next year.Elsewhere, Trade Desk surged 22.5 per cent following a report that OpenAI had held early discussions with the advertising technology company regarding the sale of advertisements.Economic data released on Thursday showed the number of Americans filing new applications for unemployment benefits remained unchanged last week.Investors are also awaiting remarks from Federal Reserve Vice Chair Michelle Bowman later in the day, ahead of the closely watched non-farm payrolls report due on Friday.On the New York Stock Exchange, declining stocks outnumbered advancers by a ratio of 2.48-to-1, while on the Nasdaq the ratio stood at 1.63-to-1.The S&P 500 recorded four new 52-week highs and two new lows, while the Nasdaq Composite registered 17 new highs and 33 new lows.
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